Friday, April 17, 2020

Nice piece on genetic correlation vs causality

This piece:
What Causes Genes?A genetic association doesn't necessarily mean a genetic cause.
Gives a good overview of why genetic correlations don't necessarily live up to their billing. (From Jaime Derringer, Ph.D.).

Addendum: As a reader mentions, this piece was apparently inspired by this study:
Population phenomena inflate genetic associations of complex social traits.

From that paper:
In conclusion, our results demonstrate some of the causal structures that may bias univariate and bivariate genetic estimates such as heritability and genetic correlations, particularly when applied to complex social phenotypes. 

3 comments:

  1. I'm surprised you didn't link the study this article was inspired by, which if you haven't should definitely give a read it's titled "population phenomena inflate genetic associates of complex social traits"

    ReplyDelete
  2. I liked that the story explained it in lay terms. Good study, though. I'll add it to this post.

    ReplyDelete
  3. I appreciate the linking of informative studies and articles but would very much like more long form written pieces on the matters relating to gwas (I quite enjoy your writing style)

    ReplyDelete