Unwashed Genes

Tuesday, January 28, 2025

"Income" GWAS

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 Yes, it's a genetic study that tries to identify genes associated with income . Yes, these people take themselves seriously and also s...
1 comment:
Wednesday, January 15, 2025

Depression GWAS spinning unfortunate result.

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 The latest depression GWAS has come out. I will focus on just one result from it: The European-only analysis identified 622 SNPs in 570 reg...
Tuesday, January 14, 2025

Eugenicists that don't use the Word

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  This filth is from a well-respected scientist in the field of behavioral genetics. I won't bother naming him, but let's read betwe...
Wednesday, January 31, 2024

Why Rare Genetic Variant Correlations Will Not Shed Light on Schizophrenia

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  As I have discussed in a previous blog post , despite claims of strong heritability from twin studies and tepid results from genetic studi...
3 comments:
Sunday, October 29, 2023

Is Behavioral Genetics a Null Field?

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 On a whim, I signed up to present a poster at the The American Society of Human Genetics (ASHG) conference in DC. That, of course, required...
Sunday, June 25, 2023

Within-Family now Fading

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Within-Family PGS was said to prove definitive causal SNP’s and even though they generally give 1 or 2% of the variance explained, this was ...
Wednesday, May 17, 2023

Review of “Innate,” by Kevin Mitchell

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“ Innate,” by the neurogeneticist Kevin Mitchell, explores the case for a genetic and neurodevelopmental origin of individual differences in...
2 comments:
Friday, March 17, 2023

“Geneticism”: The Making of a New ism

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I cringed a bit when I first saw this  paper: Nurtured Genetics: Prenatal Testing and the Anchoring of Genetic Expectancies Any time there i...
Tuesday, March 7, 2023

Study Shows That Genetically Identical Fish Can Have Lasting Behavioral Differences.

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 This is an interesting study: The Emergence and Development of Behavioral Individuality in Clonal Fish   The study monitored the “behavior”...
Monday, February 27, 2023

Within Family Studies not Finding What They are Claiming

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 More evidence that genome wide association studies (GWAS) find nothing but pop strat and noise. This study debunks the idea that you can lo...
Monday, June 6, 2022

The Use of Genetic Research to Justify Racism

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 This is a piece I wrote about the Buffalo mass shooter , who justified his actions in part by citing genetic studies. Some of these were ob...
Saturday, April 30, 2022

Dog Breed Myths

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“Thus, dog breed is generally a poor predictor of individual behavior and should not be used to inform decisions relating to selection of a ...
2 comments:
Thursday, February 17, 2022

Another ADHD "Meta-Analysis" Makes Genetic Claims for the Disorder, But Shows the Opposite.

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 The latest ADHD GWAS is available in pre-print : Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and im...
Saturday, February 5, 2022

Genetic Studies of Schizophrenia to Date Fail to Find Anything of Substance

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 This Study  compiles the results of genetic studies (GWAS) for Schizophrenia to date: What genes are differentially expressed in individual...
Thursday, December 9, 2021

New Video on Psychiatric Twin Studies

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 A second video with Jay Joseph, this time talking about his specialty: twin studies . We focus specifically on psychiatric twin studies and...
Wednesday, October 20, 2021

New YouTube Channel with Jay Joseph

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 Psychologist, author and twin study skeptic Jay Joseph and I are collaborating on a YouTube channel called “Genetic Illusions.” Our first v...
Saturday, September 11, 2021

Polygenic Risk Score is Absolutely Useless for Predicting Schizophrenia

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  This Study   used the best polygenic risk score (PRS) to try and predict schizophrenia for a large group of individuals. Let's just cu...
5 comments:
Monday, September 6, 2021

My Review of Kathryn Paige Harden's "The Genetic Lottery "

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Every few years, the scant evidence for genetic determinism will be promoted and sold in book form. In 2018, it was Robert Plomin’s “Bluepri...
25 comments:
Saturday, January 2, 2021

The “Genetics” of Schizophrenia

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 I have several posts on here related to schizophrenia and the claimed genetics of this psychiatric disorder and I thought it would be usefu...
3 comments:
Friday, December 18, 2020

Another Schizophrenia Twin Study That Only Looks Good When You Skim The Results

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  In medical school, my Psychiatry Residency, and even the Psychiatry Board Exams, the concordance rate noted for Schizophrenia was 50%. The...
Tuesday, December 15, 2020

Old Schizophrenia Twin Study That Tells a Different Story

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  This study of Finnish Twins is originally from 1984: Psychiatric Hospitalization in Twins I think it makes some interesting points and I...
6 comments:
Wednesday, December 9, 2020

Interesting Study Related to Cognitive Decline from Schizophrenia

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  This study assessed whether cognitive decline from Schizophrenia has a genetic component.  Schizophrenia polygenic risk predicts general c...

Wake Up Call for Insomnia GWAS

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Here is another GWAS , this time for insomnia, that I think buries the lead: Genome-wide meta-analysis of insomnia in over 2.3 million indiv...

Bipolar Genetics Makes No Progress

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Nice critique by Peter Simons of a genetic study for bipolar disorder among Han Chinese with the diagnosis  of Bipolar Disorder (original st...
Tuesday, December 1, 2020

The Unembarrassed Bot

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 A shortcutting of the usual GWAS is a bot that simply cranks out a Manhattan plot with no further analysis. While, those who do traditional...
Saturday, November 28, 2020

If You Can't Make it Happen for Schizophrenia

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  This is an expansion of a previous Schizophrenia GWAS: Mapping genomic loci prioritises genes and implicates synaptic biology in schizophr...
Friday, November 13, 2020

Genetic homogeneity does not reduce individuality (in fish)

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 This Study  takes genetically identical fish and puts them in indentical environments and demonstrates that they show a lot of individualit...
1 comment:
Saturday, October 31, 2020

Genes for Walking at a Brisk Pace (yes, this is real)

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  Another absurd GWAS : Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health a...

Yet Another Study Showing that Polygenic Scores are Confounded by Population Stratification

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  Another study related to height PGS: Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide ass...
Sunday, September 20, 2020

GWAS Meta-analyis for Bipolar Disorder Gives Glowing Analysis, but is impossible to Interpret (Again)

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  A brief review of t his GWAS for Bipolar Disorder: Genome-wide association study of over 40,000 bipolar disorder cases provides novel bio...
Saturday, September 12, 2020

Weekend at Bernie's for Behavioral Genetics

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Here is what I think is an attempt by Paige Harden at a behavioral genetics pivot : “Reports of My Death Were Greatly Exaggerated”: Behavior...
Tuesday, August 25, 2020

Parental Wealth is Pop Strat

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  This paper discusses how parental wealth is a strongly prone to assortative mating.  ...parental wealth homogamy is high at the very top o...
2 comments:
Sunday, August 23, 2020

The Tarot of Reading Neuroimaging

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 I'm linking to this piece discussing the lack of consistency among researchers reading and interpreting Neuroimaging studies, because I...
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